Persistent exercise limitation after successful pulmonary endoarterectomy: frequency and determinants

Respiratory Research

Table 2 Hemodynamic and respiratory variables 12 months after PEA in the whole group and in those with or without reduced exercise capacity (defined as Bruce protocol distance < 400 m)

	Whole group	< 400 m	≥400 m	p value
mPAP, mmHg	23 ± 67	25 ± 8	21 ± 6	< 0.001
CI, L/min/m²	2.7 ± 0.5	2.6 ± 0.5	2.7 ± 0.5	0.05
RVEF, %	38 ± 8	36 ± 9	39 ± 7	< 0.05
PVR, dyne _* s/cm⁵	249 ± 135	301 ± 170	213 ± 89	< 0.0001
PCa, mL/mmHg	2.85 ± 1.09	2.37 ± 0.87	3.19 ± 1.09	< 0.0001
TAPSE, mm	15.9 ± 2.8	15.6 ± 2.8	16.1 ± 2.8	NS
VC, L	3.31 ± 1.00	2.84 ± 0.76	3.63 ± 1.01	< 0.0001
VC, % pred.	100 ± 19	99 ± 21	101 ± 17	NS
TLC, L	5.35 ± 1.35	4.92 ± 1.10	5.63 ± 1.43	< 0.001
TLC, % pred.	95 ± 15	94 ± 16	95 ± 14	NS
FEV₁, L	2.37 ± 0.77	1.98 ± 0.59	2.63 ± 0.78	< 0.0001
FEV₁, % pred.	92 ± 19	90 ± 22	94 ± 17	NS
FEV₁/VC, %	72 ± 8	70 ± 8	73 ± 7	< 0.05
D_Lco_, mL/min/mmHg	5.55 ± 1.66	4.65 ± 1.32	6.14 ± 1.59	< 0.0001
D_Lco, % pred.	68 ± 15	63 ± 14	72 ± 14	< 0.001
HbSaO₂, %	97 ± 2	96 ± 2	97 ± 1	< 0.0001
HR, bpm	84 ± 12	86 ± 12	82 ± 12	< 0.05

Data are presented as mean ± sd. CI cardiac index, DLco single breath carbon monoxide diffusing capacity, FEV1 forced expiratory volume in 1 s, HbSaO₂ pulse oximetry arterial oxygen saturation, HR heart rate, mPAP mean pulmonary arterial pressure, PCa pulmonary arterial compliance, PVR pulmonary vascular resistence, RVEF right ventricular ejection fraction, TAPSE tricuspid annular plane systolic excursion, TLC total lung capacity, VC vital capacity

ISSN: 1465-993X