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Table 5 AUEC0‐24 for plasma cortisol on Day 14

From: Efficacy and safety of AZD7594, an inhaled non-steroidal selective glucocorticoid receptor modulator, in patients with asthma: a phase 2a randomized, double blind, placebo-controlled crossover trial

Dose

n

Geometric mean ratio to baseline compared to placebo (95% CI)

p‐value

placebo

14

  

58 μg

9

1.03 (0.90‐1.19)

0.6342

250 μg

9

1.02 (0.88‐1.18)

0.7620

800 μg

9

0.91 (0.79‐1.05)

0.2008

  1. AUEC 0‐24 Area under plasma concentration time curve from time zero to 24 hours after dose administration, CI confidence Interval