Gasometric gradients between blood obtained from the pulmonary artery wedge and pulmonary artery positions in pulmonary arterial hypertension

Table 3 Differences between pulmonary artery wedge and mixed venous blood in the three groups of patients

Variable	Group 1 pulmonary arterial hypertension	Groups 2–5 pulmonary hypertension	Control group	P (ANOVA / Chi square)
n (%)	65 (50.0)	40 (30.8)	25 (19.2)
pH	0.13 ± 0.07	0.10 ± 0.09	0.09 ± 0.06	0.05
pCO₂ (mmHg)	− 14.7 ± 6.6	−14.2 ± 8.0	−12 ± 6.0	0.34
pO₂ (mmHg)	64.9 ± 53.4	58.0 ± 47.4	42.7 ± 27.0	0.14
pO₂ ^a (mmHg)	42.5 ± 24.7	36.4 ± 21.3	40.9 ± 26.5	0.70
HCO₃- (mmoL/L)	− 3.4 ± 1.7	−3.0 ± 1.4	− 2.9 ± 1.3	0.33
O₂Hb (%)	25.3 ± 9.3	23.7 ± 9.6	21.0 ± 6.3	0.12
O₂Hb ^a (%)	22.2 ± 9.0	25.1 ± 6.7	21.9 ± 6.1	0.39
COHb (%)	0.16 ± 0.40	0.09 ± 0.41	0.21 ± 0.53	0.55
COHb ^b (%)	0.17 ± 0.41	0.09 ± 0.42	0.22 ± 0.56	0.55
metHb (%)	−0.12 ± 0.42	−0.11 ± 0.43	0.12 ± 0.27	0.04
Hb (g/dL)	− 0.11 ± 0.74	−0.19 ± 0.50	0.10 ± 0.61	0.20
Lactate (mmoL/L)	0.12 ± 0.13	0.10 ± 0.14	0.06 ± 0.08	0.12

Definition of Abbreviations: CI: confidence interval, COHb: carboxyhemoglobin, Hb: hemoglobin, HCO₃-: bicarbonate, metHb: methemoglobin, O₂Hb: oxyhemoglobin, pCO₂: partial pressure of carbon dioxide, pO₂: partial pressure of oxygen
Data are expressed as mean ± SD
^aPatients not on Oxygen supplementation
^bnonsmokers patients only

ISSN: 1465-993X