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Fig. 3 | Respiratory Research

Fig. 3

From: Circular RNAs: a rising star in respiratory diseases

Fig. 3

Biological functions of circRNAs. CircRNAs act as miRNA sponge to decrease the expression level of miRNA via miRNA response elements and further to regulate the expression of downstream mRNA. CircRNAs could regulate the transcription of parental genes and adjust its variable splicing. CircRNAs could combine with RBPs to regulate the post-transcriptional process. CircRNAs could directly encode protein. CircRNAs-derived pseudogenes could retrotranscribed and reinserted into the host genome

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