Fig. 7

CTNNB1 is an important target in the anti-metastatic function of SOX30 in ADC patients. a SOX30 and CTNNB1 expressions were analyzed at 48 h after transfected with empty-vector, SOX30 and co-transfected with SOX30 and CTNNB1 plasmids in SPC-A-1 cells by WB. b, c The cell migration and invasion were determined at 48 h after transfected with empty-vector, SOX30 and co-transfected with SOX30 and CTNNB1 plasmids in SPC-A-1 cells by transwell assays. The numbers of migrated or invaded cells were quantified by average count of five random microscopic fields. **, p < 0.01. The p value was obtained by Student’s t-tests. d The mechanism illustration for different roles on tumor metastasis of SOX30 in ADC and SCC patients