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Table 2 Clinical and laboratory variables

From: Clinical variables predicting the risk of a hospital stay for longer than 7 days in patients with severe acute exacerbations of chronic obstructive pulmonary disease: a prospective study

Variables Normal LHS (≤ 7 days) (n = 213) Prolonged LHS (>  7 days) (n = 224) p value
Respiratory rate, b/min 24 [20; 28] 24 [20; 28] 0.482
Heart rate, b/min 91.5 [83; 102.5] 95 [80; 108] 0.293
Body temperature, °C 36.4 [35.9; 37] 36.3 [36; 36.8] 0.569
SBP, mmHg 140 [120; 155] 135.5 [124; 156] 0.719
DBP, mmHg 75 [68; 86] 76 [68; 87] 0.895
Laboratory variables at admission
 Leucocytes, 109/l 10.1 [7.9; 14] 10.1 [7.7; 13.6] 0.464
 Haematocrit, % 43 [39; 47] 43 [40; 47] 0.425
 Haemoglobin, g/L 138 [125; 151] 140 [127; 153] 0.738
 C-reactive protein, mg/dL 4.1 [1.3; 10.1] 3.6 [1.1; 9.7] 0.412
 Glucose, mg/dL 123 [108; 152.7] 126 [107.7; 166] 0.485
 Creatinine, mg/dL 0.9 [0.8; 1.1] 0.9 [0.7; 1.1] 0.041
Laboratory variables at day 3
 Leucocytes, 109/l 10.6 [8.3; 13.4] 10.7 [8.1; 13] 0.922
 Haematocrit, % 41 [38; 44] 41 [37; 45] 0.685
 Haemoglobin, g/L 131 [119; 143] 131 [118; 143] 0.436
 C-reactive protein, mg/dL 1.4 [0.5; 4.1] 0.9 [0.3; 2.9] 0.161
 Glucose, mg/dL 116 [96; 153] 123 [100.5; 161] 0.096
 Creatinine, mg/dL 0.9 [0.7; 1.2] 0.8 [0.7; 1] 0.027
Treatments during hospitalisation
 Systemic corticosteroids, % 91 92 0.631
 Antibiotics, % 84 88 0.304
 Number of antibiotics used, 0/1/≥2, % 16/64/20 12/64/24 0.383
 Duration of antibiotic treatment, days 7 [5; 10] 7 [6; 10] 0.375
 Penicillins, % 16 19 0.498
 Fluoroquinolones, % 57 45 0.023
 Macrolides, % 2 2 > 0.999
 Cephalosporins, % 1 5 0.035
 Carbapenems, % 0 1 0.501
  1. Data are shown as number of patients (percentage) or medians [1st quartile; 3rd quartile], unless otherwise stated. Percentages are calculated for non-missing data
  2. Systemic corticosteroids include methylprednisolone; penicillins include amoxicillin and amoxicillin/clavulanate; fluoroquinolones include ciprofloxacin, moxifloxacin and levofloxacin; macrolides include azithromycin and clarithromycin; cephalosporins include ceftriaxone, cefotaxime, cefuroxime and cefepime; and carbapenems include meropenem
  3. Abbreviations: DBP and SBP indicate diastolic and systolic blood pressure, respectively; LHS, length of hospital stay