Table 2 Clinical and laboratory variables
Variables | Normal LHS (≤ 7 days) (n = 213) | Prolonged LHS (> 7 days) (n = 224) | p value |
|---|---|---|---|
Respiratory rate, b/min | 24 [20; 28] | 24 [20; 28] | 0.482 |
Heart rate, b/min | 91.5 [83; 102.5] | 95 [80; 108] | 0.293 |
Body temperature, °C | 36.4 [35.9; 37] | 36.3 [36; 36.8] | 0.569 |
SBP, mmHg | 140 [120; 155] | 135.5 [124; 156] | 0.719 |
DBP, mmHg | 75 [68; 86] | 76 [68; 87] | 0.895 |
Laboratory variables at admission | |||
Leucocytes, 109/l | 10.1 [7.9; 14] | 10.1 [7.7; 13.6] | 0.464 |
Haematocrit, % | 43 [39; 47] | 43 [40; 47] | 0.425 |
Haemoglobin, g/L | 138 [125; 151] | 140 [127; 153] | 0.738 |
C-reactive protein, mg/dL | 4.1 [1.3; 10.1] | 3.6 [1.1; 9.7] | 0.412 |
Glucose, mg/dL | 123 [108; 152.7] | 126 [107.7; 166] | 0.485 |
Creatinine, mg/dL | 0.9 [0.8; 1.1] | 0.9 [0.7; 1.1] | 0.041 |
Laboratory variables at day 3 | |||
Leucocytes, 109/l | 10.6 [8.3; 13.4] | 10.7 [8.1; 13] | 0.922 |
Haematocrit, % | 41 [38; 44] | 41 [37; 45] | 0.685 |
Haemoglobin, g/L | 131 [119; 143] | 131 [118; 143] | 0.436 |
C-reactive protein, mg/dL | 1.4 [0.5; 4.1] | 0.9 [0.3; 2.9] | 0.161 |
Glucose, mg/dL | 116 [96; 153] | 123 [100.5; 161] | 0.096 |
Creatinine, mg/dL | 0.9 [0.7; 1.2] | 0.8 [0.7; 1] | 0.027 |
Treatments during hospitalisation | |||
Systemic corticosteroids, % | 91 | 92 | 0.631 |
Antibiotics, % | 84 | 88 | 0.304 |
Number of antibiotics used, 0/1/≥2, % | 16/64/20 | 12/64/24 | 0.383 |
Duration of antibiotic treatment, days | 7 [5; 10] | 7 [6; 10] | 0.375 |
Penicillins, % | 16 | 19 | 0.498 |
Fluoroquinolones, % | 57 | 45 | 0.023 |
Macrolides, % | 2 | 2 | > 0.999 |
Cephalosporins, % | 1 | 5 | 0.035 |
Carbapenems, % | 0 | 1 | 0.501 |