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Table 4 Correlation between changes in ELISA measurements and lung function

From: Serum AGE/RAGEs as potential biomarker in idiopathic pulmonary fibrosis

Correlations Change of PFT r R2 P-value
Δ sRAGE FVC 0.437 0.191 0.042*
DLCO 0.586 0.343 0.005**
TLC 0.412 0.170 0.057
Δ AGEs FVC −0.452 0.204 0.027*
DLCO −0.747 0.557 0.000**
TLC −0.486 0.237 0.022*
Δ Ratio FVC −0.479 0,230 0.018*
DLCO −0.704 0.495 0.000**
TLC −0.352 0.124 0.100
  1. AGE advanced glycation end-product, DLCO diffusing capacity for carbon monoxide, FVC forced vital capacity, PFT pulmonary function test, r correlation coefficient, R2 coefficient of determination, sRAGE soluble receptor for advanced glycation end-products, TLC Total lung capacity. (*) p-value < 0.05, (**) p-value < 0.01