Serum AGE/RAGEs as potential biomarker in idiopathic pulmonary fibrosis

Respiratory Research

Table 4 Correlation between changes in ELISA measurements and lung function

Correlations	Change of PFT	r	R²	P-value
Δ sRAGE	FVC	0.437	0.191	0.042*
	DLCO	0.586	0.343	0.005**
	TLC	0.412	0.170	0.057
Δ AGEs	FVC	−0.452	0.204	0.027*
	DLCO	−0.747	0.557	0.000**
	TLC	−0.486	0.237	0.022*
Δ Ratio	FVC	−0.479	0,230	0.018*
	DLCO	−0.704	0.495	0.000**
	TLC	−0.352	0.124	0.100

AGE advanced glycation end-product, DLCO diffusing capacity for carbon monoxide, FVC forced vital capacity, PFT pulmonary function test, r correlation coefficient, R² coefficient of determination, sRAGE soluble receptor for advanced glycation end-products, TLC Total lung capacity. (*) p-value < 0.05, (**) p-value < 0.01

ISSN: 1465-993X