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Table 3 ELISA measurements and lung function from IPF patients at 3-year interval

From: Serum AGE/RAGEs as potential biomarker in idiopathic pulmonary fibrosis

Patient characteristics Initial 3 yrs. p-value
sRAGE (pg/ml) 461.53 ± 191.77 375.78 ± 143.25 0.029*
AGEs (μg/ml) 19.07 ± 8.63 17.19 ± 8.45 0.340
Ratio (‰) 52.58 ± 34.58 41.13 ± 14.91 0.079
% FVC 89.21 ± 19.50 79.14 ± 20.63 0.001**
% DLCO 57.84 ± 11.54 48.68 ± 12.73 0.000**
% TLC 87.22 ± 16.89 76.47 ± 15.57 0.000**
  1. Data represent the mean ± SD, AGE advanced glycation end-product, DLCO diffusing capacity for carbon monoxide, FVC forced vital capacity, sRAGE soluble receptor for advanced glycation end-products, TLC Total lung capacity. (*) p-value < 0.05, (**) p-value < 0.01