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Table 1 Population characteristics

From: From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function

 

LifeLines Cohort

Number

658

Males, N (%)

375 (57,0)

Age, years (range)

46 (22–79)

Pack year, years, mean (range)

20,6 (5–100)

FEV1/FVC (%), mean (range)

71,7 (40,1 – 92,4)

FEV1(%pred)*, mean (range)

94,4 (47,7 – 138,4)

COPD cases, N (%)

279 (42,4)

GOLD COPD Stage ≥ 2†, N (%)

102 (15,6)

  1. * Calculated with GLI-2012 if possible
  2. † COPD GOLD stage > 2 (FEV1/FVC < 70% and FEV1 between 50 and 80% of predicted)
  3. COPD, Chronic Obstructive Pulmonary Disease; FEV1, Forced Expiratory Volume in 1 s; FVC, Forced Vital Capacity