Table 1 Demography, baseline (Pre-bronchodilator) and maximal (Post-bronchodilator) pulmonary function tests for 130 Stratum 1 (healthy), 114 Stratum 2, 131 Stratum 3 and 39 Stratum 4 subjects
Stratum 1 (Healthy) | Stratum 2 | Stratum 3 | Stratum 4 | P value | |
|---|---|---|---|---|---|
N = 130 | N = 114 | N = 131 | N = 39 | ||
Demography | |||||
Age, yrs | 47.8 (16.9) | 53.7 (8.1) | 62 (8.1) | 62.6 (7.7) | < 0.0001 |
BMI, kg/m2 | 27.4 (5.5) | 28.4 (5.3) | 26.3 (4.8) | 23.8 (4.9) | < 0.0001 |
Gender, (Male/Female %) | 41.5/58.5 | 49.1/50.9 | 61.8/38.2 | 69.2/30.8 | 0.039 |
Race, Caucasian/ African American/ Other (%) | 71.5/16.2/12.3 | 45.6/48.2/6.1 | 77.1/19.1/3.8 | 71.8/20.5/7.7 | < 0.0001 |
Baseline lung functiona | |||||
FEV1% predicted | 100 (13) | 93 (14) | 64 (18) | 34 (7) | < 0.0001 |
FVC % predicted | 99 (11) | 98 (14) | 87 (19) | 67 (16) | < 0.0001 |
FEV1/FVC × 100 | 80 (7) | 75 (6) | 56 (8) | 40 (11) | < 0.0001 |
Maximal lung functionb | |||||
FEV1% predicted | 102 (11) | 99 (14) | 73 (16) | 40 (7) | < 0.0001 |
FVC % predicted | 99 (10) | 100 (13) | 96 (18) | 78 (17) | < 0.0001 |
FEV1/FVC × 100 | 82 (6) | 78 (5) | 58 (8) | 41 (11) | < 0.0001 |