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Fig. 1 | Respiratory Research

Fig. 1

From: Inhaled furosemide for relief of air hunger versus sense of breathing effort: a randomized controlled trial

Fig. 1

Breathing circuit. The Breathing Circuit was identical for air hunger (AH) test and work/effort (WE) test, except that the external resistance was removed in the AH test. To elicit AH, CO2 was added to the flow of fresh gas into the bag and this flow was fixed at baseline alveolar ventilation. To elicit WE, individuals were instructed to empty the bag with each breath while the flow of fresh bag into the bag was increased and CO2 was added to maintain normocapnia.  PETCO2 = end tidal PCO2

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