Fig. 1
From: What have we learned from observational studies and clinical trials of mild to moderate COPD?

Proposal of treatment algorithm for the management of GOLD 1–2 COPD patients. COPD: chronic obstructive pulmonary disease; ACO: asthma-COPD overlap; LAMA: long acting anti muscarinic; LABA: long acting b-2 agonists; ICS: inhaled corticosteroids