Table 1 Population characteristics of adult cohorts
| Â | SAPALDIA2 T1, 2001 | SAPALDIA3 T2, 2010 | ECRHS 2Â T1, 1998 | ECRHS 3Â T2, 2008 | NFBC 1966Â T1, 1997 | NFBC 1966Â T2, 2012 | |
|---|---|---|---|---|---|---|---|
N | 561 | 561 | 267 | 267 | 248 | 248 | |
Female, % | 48.3 | 48.3 | 52.1 | 52.1 | 49.8 | 48.2 | |
Age (years), mean (SD) | 50.4 (10.8) | 58.7 (10.7) | 44.0 (6.0) | 55.0 (6.0) | 31.0 (0.3) | 46.3 (0.4) | |
Height (cm), mean (SD) | 170.2 (9.2) | 169.5 (9.3) | 170.0 (9.0) | 170.0 (9.0) | 172.0 (8.7) | 172.0 (8.6) | |
Weight (kg), mean (SD) | 73.9 (14.8) | 75.6 (15.6) | 74 (15.0) | 77 (16.0) | 72.1 (12.8) | 80.8 (15.3) | |
Body mass index (kg/m2), mean (SD) | 25.4 (4.2) | 26.2 (4.6) | 25.2 (4.2) | 26.8 (4.5) | 24.3 (3.6) | 27.2 (4.5) | |
Smoking status, % | |||||||
 Ex-smoker | 52.0 | 63.0 | 54.7 | 69.3 | 46.8 | 69.2 | |
 Current smoker | 48.0 | 37.0 | 45.3 | 30.7 | 53.2 | 30.8 | |
Pack-years, mean (SD)a | 20.4 (20.2) | 22.6 (22.1) | 17 (17.0) | 20 (21.0) | 7.7Â (5.9) | 11.0Â (9.6) | |
Education (%) | |||||||
SAPALDIA | ECRHS & NFBC | Â | Â | Â | Â | Â | Â |
Lowb | ≤16 yearsc | 5.0 | 4.0 | 10.9 | 10.9 | 0.4 | 0.4 |
Intermediate | 17–19 years | 66.0 | 67.0 | 30.5 | 30.5 | 61.9 | 61.9 |
High | 20+ years | 29.0 | 29.0 | 58.6 | 58.6 | 37.7 | 37.7 |
FVC (L), mean (SD) | 4.4 (1.0) | 4.1 (1.0) | 4.4 (1.0) | 4.0 (1.0) | 4.9 (1.0) | 4.6Â (0.9) | |
FVC % Predictedd, mean (SD) | 106.2 (13.4) | 106.0 (13.4) | 100.7 (13.0) | 99.2 (13.5) | 101.8 (10.8) | 104.1 (11.2) | |
FEV1 (L), mean (SD) | 3.3 (0.8) | 3.0 (0.8) | 3.4 (0.8) | 3.0 (0.7) | 4.1 (0.8) | 3.5(0.7) | |
FEV1% Predictedd, mean (SD) | 99.3 (14.2) | 97.9 (16.0) | 96.5 (13.7) | 93.8 (14.2) | 102.1 (11.5) | 100.1 (11.8) | |
FEV1/FVC, mean (SD) | 0.8 (0.08) | 0.7 (0.08) | 0.8 (0.06) | 0.8 (0.1) | 0.8Â (0.05) | 0.8Â (0.06) | |
FEV1/FVC % Predictedd, mean (SD) | 93.2 (9.4) | 92.0 (9.9) | 95.4 (7.7) | 94.2 (7.7) | 99.9 (6.8) | 95.8 (7.0) | |
CRP (mg/L), mean (SD) | 1.92 (2.8) | – | – | – | – | – | |
AAT (g/L), mean (SD) | 1.27 (0.2) | – | – | – | – | – | |
COPD, defined by FEV1/FVC < LLNe | 15.3 | 17.1 | 10.5 | 12.7 | 2.2 | 11.4 | |
Doctor-diagnosed asthma, % | 15.7 | 19.1 | 14.6 | 17.2 | 10.5 | 17.1 | |
Respiratory medication (last 12Â months), % | 22.5 | 25.8 | 12.4 | 14.3 | NA | NA | |
Spirometer brand and model, % | |||||||
 SensorMedics 2200 | 100.0 | – | – | – | – | – | |
 EasyOne NDD Medical Technologies | – | 100.0 | – | 100.0 | – | – | |
 SensorMedics 2400 | – | – | 36.0 | – | – | – | |
 Jaeger Pneumotach | – | – | 16.1 | – | – | – | |
 Biomedin Spirometer | – | – | 47.9 | – | – | – | |
 Vitalograph P Model | – | – | – | – | 100.0 | – | |
 MasterScreen Pneumo | – | – | – | – | – | 100.0 | |