Fig. 6

Impact of silica and treatments with MSCs or EVs in lung remodeling and lung mechanics. a, b Box plot representation of collagen fiber content (min to max) in the alveolar septa (a) or inside the granuloma (b). Values indicate measurements from 10 random fields of 5 animals per group *Significantly different from control group (labeled C). **Significantly different from SIL-Sal group (p < 0.05). c Static lung elastance values in box plot representation (min to max). d Stacked bars represent viscoelastic (ΔP2) and resistive (ΔP1) pressures. Fifteen measurements were taken from each animal, and 6–10 animals were analyzed per group. *Significantly different from control group (labeled C). **Significantly different from SIL-Sal group (p < 0.05)