Fig. 14
From: Effects and molecular mechanisms of intrauterine infection/inflammation on lung development
Quantification of NLRP3, VEGF and Collagen I from the fetal and neonatal rat lung. NLRP3 expression was significantly increased at E19, E21 and P1, P3, P14 in intrauterine infection group compared with control while it was not significantly different between the two groups at E17, P7 a. Western blot assays of the fetal and neonatal rats lung tissues showed VEGF expression was significantly decreased at E19, E21 and P1, P3, P7 in intrauterine infection group compared with control while it was not significantly different between the two groups at E17 and P14 b. Densitometric analysis showed Collagen I expression was significantly increased in intrauterine infection group compared with control, except at E17 c. *P < 0.05; **P < 0.01, vs. control group