Table 1 Patient characteristics
| Â | Total IIP population | IPF subpopulation | Paired IIP | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | S | AE | p value | S | AE | p value | S | AE | p value |
n | 29 | 68 | Â | 11 | 28 | Â | 28 | 28 | Â |
Age (mean SD) | 69 (8) | 71 (7) | 0.206 | 67 (8) | 71 (7) | 0.150 | 68.3 (7.6) | 68.3 (7.6) | NA |
Female gender (n %) | 6 (21%) | 12 (18%) | 0.726 | 0 (0%) | 0 (0%) | NA | 6 (21%) | 6 (21%) | NA |
Smokers (n %) | |||||||||
 Current | 0 (0%) | 1 (1%) | 0.514 | 0 (0%) | 0 (0%) | NA | 0 (0%) | 0 (0%) | NA |
 Ex | 23 (79%) | 50 (74%) | 0.548 | 9 (82%) | 23 (82%) | 0.981 | 22 (79%) | 22 (79%) | |
 Never | 6 (21%) | 17 (25%) | 0.649 | 2 (18%) | 5 (18%) | 0.981 | 6 (21%) | 6 (21%) | |
FVC %pred (mean SD) | 79 (27) | 56 (19) | < 0.0001 | 73 (13) | 55 (16) | 0.0014 | 77 (26) | 59 (24) | < 0.0001 |
VC (%pred), mean SD | 78.7 (26.0) | 54.6 (18.9) | < 0.0001 | 72.7 (13.5) | 53.6 (16.0) | 0.0023 | 76 (25) | 57 (23) | < 0.0001 |
Time from IIP diagnosis to AE admission, months (median IQR) |  | 12 (3–38) |  |  | 29 (11–40) |  |  | 24 (8–38) |  |
Treatment duration from AE admission, days (median IQR) |  | 8 (3–14) |  |  | 7 (2–12) |  |  | 8 (4–16) |  |
Non-survivors at 100Â days after AE admission (n %) | Â | 37 (54%) | Â | Â | 13 (46%) | Â | Â | 15 (54%) | Â |
Time to death after AE admission, days (median IQR) |  | 15 (6–35) |  |  | 15 (4–43) |  |  | 17 (10–30) |  |