Table 1 Characteristics of the subjects
From: Plasma YKL-40 and NGAL are useful in distinguishing ACO from asthma and COPD
| Â | Control(50) | Asthma(124) | ACOS(102) | COPD(147) |
|---|---|---|---|---|
Age, years | 49.60 ± 18.14 | 48.49 ± 12.25 | 62.54 ± 9.07 | 67.56 ± 9.18 |
BMI,kg.m−2 | 23.50 ± 1.11 | 24.43 ± 1.67 | 25.55 ± 1.21 | 22.43 ± 1.56 |
Smoker(former/current/never), n | 0/0/50 | 22/49/53 | 14/78/10 | 34/102/11 |
Pack-years | / | 13.62 ± 13.98 | 46.51 ± 15.78 | 39.31 ± 14.34 |
Sex(female/male), n | 22/28 | 69/55 | 62/40 | 48/99 |
Years of biomass exposure≥10 (≥100 h/year) | 0 | 23 | 45 | 72 |
Postbronchodialator | ||||
 FEV1, L | 2.63 ± 0.23 | 2.10 ± 0.16 | 1.97 ± 0.17 | 1.67 ± 0.23 |
 FVC, L | 3.22 ± 0.25 | 2.77 ± 0.22 | 3.01 ± 0.26 | 2.66 ± 0.33 |
 FEV1% pre | 95.40 ± 7.65 | 73.67 ± 5.53 | 70.85 ± 5.62 | 58.95 ± 9.05 |
 FVC% pre | 98.02 ± 7.10 | 81.42 ± 6.91 | 80.49 ± 3.25 | 74.04 ± 6.72 |
 FEV1/FVC | 81.69 ± 4.48 | 75.91 ± 4.01 | 65.24 ± 2.86 | 62.65 ± 3.34 |
Response to bronchodilator | ||||
 % Change in FEV1,% | 2.83 ± 1.04 | 16.91 ± 1.83 | 15.16 ± 1.04 | 6.26 ± 1.24 |
 Change in FEV1,ml | 72.42 ± 27.78 | 303.68 ± 37.70 | 259.64 ± 30.68 | 99.10 ± 26.31 |
SQRG score | / | 39.51 ± 4.32 | 44.65 ± 3.66 | 52.27 ± 3.86 |
%LAA-950, % | 3.24 ± 1.31 | 6.85 ± 2.26 | 11.49 ± 2.99 | 21.52 ± 5.21 |
Blood eosinophils, 108/L | 2.45 ± 1.11 | 3.45 ± 0.76 | 3.05 ± 0.87 | 2.75 ± 1.30 |
Blood neutrophil, 109/L | 3.59 ± 1.57 | 3.94 ± 1.43 | 4.43 ± 1.31 | 5.63 ± 2.08 |
Serum creatinine (umol/L) | 73.40 ± 20.8 | 76.79 ± 15.94 | 78.08 ± 19.02 | 75.22 ± 15.38 |