Table 3 Summary of urine PK parameters (Amount excreted Ae) by treatment
From: The topical study of inhaled drug (salbutamol) delivery in idiopathic pulmonary fibrosis
Interval | Salbutamol Treatment | N | Mean (μg) | Median (μg) | Min (μg) | Max (μg) | Median Percent of Dose (%) |
|---|---|---|---|---|---|---|---|
0-30 min | 1.5 μm (50 μg) | 7 | 1.5 | 1.2 | 0.5 | 4 | 3 |
6 μm (50 μg) | 7 | 1.2 | 1 | 0.7 | 2.8 | 2.4 | |
Neb (2.5Â mg) | 7 | 17.4 | 14.4 | 0.7 | 46.3 | 0.7 | |
pMDI (400 μg) | 8 | 3.8 | 4.2 | 0.9 | 6.3 | 1 | |
0-8 h | 1.5 μm (50 μg) | 6 | 8.1 | 6.9 | 2.7 | 19.4 | 16.2 |
6 μm (50 μg) | 7 | 12.8 | 7.6 | 4.6 | 29.2 | 25.6 | |
Neb (2.5Â mg) | 7 | 51.4 | 64.1 | 6.7 | 90.1 | 2.1 | |
pMDI (400 μg) | 8 | 16.5 | 17.6 | 4.5 | 28.7 | 4.1 |