Fig. 4
From: PM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway
Effects of the Shh pathway on HBSMC migration. a and d HBSMC migration in response to increasing concentrations of Shh. b and e Cyclopamine significantly inhibited r-Shh-induced HBSMC migration. c and f Cyclopamine significantly inhibited TAPM2.5- and WSPM2.5-induced HBSMC migration. g and h siRNA knockdown of Gli1 or Snail significantly inhibited TAPM2.5- and WSPM2.5-induced HBSMC migration. *, P < 0.05; **, P < 0.001 compared with the control group