Table 1 Baseline lung function for mice studies completed in control and treated wildtype (WT) and TLR4 (TLR4 −/−) mutant mice. Baseline lung function measurements taken before methacholine challenge were not significantly different between treatments in WT and TLR4−/− mice. Greater Raw values were measured for all TLR4−/− mice compared to WT mice of the same treatment, indicating that overall, this mouse strain had more sensitive airways

Treatment

Mouse strain

WT

TLR4−/−

WT

TLR4−/−

WT

TLR4−/−

WT

TLR4−/−