Fig. 4
Effect of SB239063 and α-tocopherol treatment on OVA-O3 mice model. Equal numbers of OVA-O3 mice were received tail vein injection of SB239063 (4 mg/kg) (DMSO as control), or oral feeding of α-tocopherol (15 IU/kg) (50% ethanol as control), or both. The phosphorylation of p38 MAPK (a) and HSP27 (b) in tracheal tissues were measured by immunoblotting; the MDA content (c) and the GSH-Px activity (d) in lung homogenates were analyzed to assess the oxidative stress. Data are shown as mean ± SEM, n = 5 in each group