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Table 3 Comparison between initial and 1-year follow-up lung function according to antinuclear antibody (ANA) positivity

From: Factors affecting treatment outcome in patients with idiopathic nonspecific interstitial pneumonia: a nationwide cohort study

 

ANA negative (n = 41)

ANA positive (n = 18)

 

Initial

Follow-up

p-value

Initial

Follow-up

p-value

FVC (%)

72.1 ± 20.6

83.2 ± 15.5

0.008

68.6 ± 19.5

76.4 ± 18.1

0.102

FEV1 (%)

80.1 ± 23.7

91.4 ± 19.7

0.005

75.4 ± 19.0

83.7 ± 19.1

0.091

DLco (%)

68.7 ± 24.9

80.8 ± 26.0

<0.001

62.9 ± 21.1

64.9 ± 23.4

0.568

  1. FVC forced vital capacity, % pred percentage of the predicted value, FEV 1 forced expiratory volume, DL CO diffusing capacity of the lung for carbon monoxide, ANA antinuclear antibody