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Fig. 2 | Respiratory Research

Fig. 2

From: A 3D epithelial–mesenchymal co-culture model of human bronchial tissue recapitulates multiple features of airway tissue remodeling by TGF-β1 treatment

Fig. 2

Histological analysis of epithelial and mesenchymal cells on culture day 21. a Hematoxylin and eosin staining, vimentin immunostaining, α-SMA immunostaining and E-cadherin immunostaining. Arrowheads indicate heavily stained fibroblast cells in the mesenchymal layer following TGF-β1 stimulation. Arrows indicate vimentin-positive basal cells in the epithelial layer following TGF-β1 stimulation. Scale bar: 50 μm. b Percentage of the vimentin-positive area in the mesenchymal layer of the tissue section. c Percentage of the vimentin-positive area in the epithelial layer of the tissue section. d Percentage of the α-SMA-positive area in the mesenchymal layer of the tissue section. e Percentage of the E-cadherin positive area in the epithelial layer of the tissue section. All data are shown as means ± SD of triplicate inserts. *p < 0.05 (Dunnett’s test against the control)

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Respiratory Research

ISSN: 1465-993X

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