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Table 2 Biomarkers associated with FEV1%

From: The value of blood cytokines and chemokines in assessing COPD

 

COPDGene

SPIROMICS

Combined

Biomarker

ß

R2 (adj)

P

ß

R2 (adj)

P

P

Eotaxin

−12.2

0.007

0.0001

−31.3

0.039

< 10−10

< 10−12

CCL26

−1.7

0.000

0.2225

−3.4

0.001

0.1095

0.0679

CCL17

0.1

0.000

0.9383

−3.7

0.001

0.1664

0.3525

IFN-γ

−6.2

0.006

0.0003

−4.5

0.002

0.0881

0.0002

IL10

−4.1

0.003

0.0072

−6.2

0.003

0.0442

0.0013

IL2

−2.8

0.002

0.0426

−7.2

0.007

0.0043

0.0016

IL6

−16.2

0.049

< 10−23

−21.1

0.042

< 10−11

< 10−34

IL8

−4.2

0.002

0.0226

−9.9

0.005

0.0091

0.0008

TNF-α

−7.0

0.006

0.0004

−6.4

0.001

0.1725

0.0003

  1. R2 (adj) is the partial amount of variance explained by the biomarker in models with clinical covariates
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Respiratory Research

ISSN: 1465-993X

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