Table 1 Autoimmune Serology Screening Panel

ANA, serum

< or =1.0 U (negative), 1.1–2.9 U (weakly positive), 3.0–5.9 U (positive) ≥ 6.0 U (strongly positive)

>1.0 U

SS-A/Ro antibody, serum IgG

<1.0 (negative)

≥1.0 (positive)

SS-B/La antibody, serum IgG

<1.0 (negative)

≥1.0 (positive)

Smith antibody, serum IgG

<1.0 (negative)

≥1.0 (positive)

RNP antibody, serum IgG

<1.0 (negative)

≥1.0 (positive)

Scl 70 antibody, serum

<1.0 (negative)

≥1.0 (positive)

Jo-1 antibody, serum IgG

<1.0 (negative)

≥1.0 (positive)

RF, serum antibodies (all classes against Fc of IgG)

<15 IU/mL

>15 IU/mL

CCP antibody, serum

<20.0 U (negative), 20.0–39.9 U (weak positive), 40.0–59.9 U (positive), ≥ 60.0 U (strong positive)

>20 U

MPO antibody, serum

<0.4 U (negative), 0.4–0.9 U (equivocal), ≥1.0 U (positive)

≥1.0 U

PR3 antibody, serum

<0.4 U (negative), 0.4–0.9 U (equivocal), ≥1.0 U (positive)

≥1.0 U

Creatinine kinase, serum

Male >18 yo: range 52–336 U/L

Female >18 yo: range 38–176 U/L

>336 U/L (male)

>176 U/L (female)

Aldolase, serum

<7.7 U/L

>7.7 U/L