Skip to main content

Table 6 Pharmacological treatment of IPF in the years 2002 – 2016a

From: Effect of smoking and comorbidities on survival in idiopathic pulmonary fibrosis

Medication

N / %

No medication

42 / 31.8

Total

 Corticosteroids

75 / 56.8

 Azathioprine

28 / 37.2

 N-acetylcysteine

30 / 40.0

 Cyclophosphamide

16 / 12.1

 Pirfenidone

6 / 4.5

 Nintedanib

3 / 2.3

 Mycophenolate mofetil

1 / 0.8

Single medication

 Corticosteroids

24 / 18.2

 N-acetylcysteine

11 / 8.3

 Pirfenidone

5 /3.8

 Nintedanib

1 /0.8

 Triple therapy b

7 /5.3

Combined with prednisone as only medication

 Azathioprine

14 / 10.6

 N-acetylcysteine

13 / 9.8

 Cyclophosphamide

8 / 6.1

After prednisone therapy

 Nintedanib

2 /1.5

Before triple therapy

 Cyclophosphamide + Corticosteroids

2 / 1.5

After triple therapy

 Pirfenidone

1 / 0.8

 Cyclophosphamide

3 / 2.3

 Mycophenolate

1 / 0.8

  1. aDiagnosis of IPF between years 2002 – 2012, while the follow-up information of medication was gathered until 16.10.2016. Reimbursement (by KELA) in Finland for pirfenidone in 1st June 2013 and for nintedanib in 1st December 2015.
  2. bTriple therapy = azathioprine, N-acetylcysteine and prednisone