Table 1 Demographics of the patients with IPF according to their smoking status
From: Effect of smoking and comorbidities on survival in idiopathic pulmonary fibrosis
Whole cohort | Ex-smoker (ES) | Current smoker (CS) | Non-smoker (NS) | p-value (between ES and CS) | p-value (between ES and NS) | |
|---|---|---|---|---|---|---|
N (%)a | 132 (100%) | 66 (50.0) | 17 (12.8) | 45 (34.1) | ||
Pack years (SD) | 25.9 (17.66) | 23.1 (18.43) | 32.9 (13.65) | 0.006 | ||
Smoking years (SD) | 25.5 (13.54) | 21.8 (12.48) | 38.1 (8.48) | <0.001 | ||
Male N (%) | 97 (73.5) | 59 (90.8) | 14 (82.4) | 20 (44.4) | 0.312 | <0.001 |
Age at diagnosis (y)(SD) | 70.5 (9.80) | 72.4 (7.95) | 58.1 (9.93) | 71.7 (8.74) | <0.001 | 0.411 |
Age at death (y) (SD) | 74.4 (9.35) | 75.8 (8.06) | 63.1 (8.13) | 76.2 (8.47) | <0.001 | 0.877 |
Median survival (mo) | 45.0 | 36.0 | 52.0 | 55.0 | 0.029 | 0.034 |
Pulmonary function tests (mean (SD)) | ||||||
FVC% (SD)b | 76.7 (18.51) | 75.6 (19.51) | 76.1 (17.48) | 78.3 (17.26) | 0.926 | 0.341 |
FEV1% (SD) | 77.0 (16.99) | 74.9 (17.64) | 75.1 (15.77) | 80.7 (16.26) | 0.866 | 0.050 |
FEV1/FVC% (SD) | 101.4 (9.68) | 100.0 (9.70) | 99.8 (11.84) | 103.7 (7.72) | 0.995 | 0.093 |
DLco% (SD)c | 56.1 (17.51) | 53.8 (16.13) | 58.9 (19.49) | 58.2 (18.98) | 0.272 | 0.139 |
CPI (SD) | 39.9 (19.96) | 41.1 (13.63) | 37.9 (14.25) | 39.1 (14.67) | 0.312 | 0.341 |
Radiological diagnoses N (%) | ||||||
Definite UIP | 79 (61.7) | 37 (46.8) | 14 (61.7) | 28 (35.4) | 0.055 | 0.553 |
Possible UIP | 28 (21.9) | 19 (67.9) | 1 (3.6) | 8 (28.6) | 0.049 | 0.261 |
Not UIP | 21 (16.4) | 10 (47.6) | 2 (11.8) | 9 (42.9) | 0.723 | 0.794 |