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Fig. 3 | Respiratory Research

Fig. 3

From: MicroRNA-181c inhibits cigarette smoke–induced chronic obstructive pulmonary disease by regulating CCN1 expression

Fig. 3

miR-181c decreased the levels of IL-6 and IL-8 in CS-exposed cells and mice. a HBECs were transfected with agomiR-181c or antagomiR-181c and then exposed to 2.5% CSE for 24 h. ELISA was performed to analyze IL-6 and IL-8 levels in cell supernatant. The levels of IL-6 and IL-8 mRNA (b) and protein (c) were measured by qRT-PCR and ELISA in PBS/Air group, scramble/CS group, agomiR-181c/CS group, and antagomiR-181c/CS group animals after 24 weeks. Data are presented as means ± SD (n = 6 per group). *p < 0.05, **p < 0.01

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