Fig. 5

a Circulating neutrophil count, (b) serum CRP and (c) serum fibrinogen over time (safety population). Raw mean and standard errors estimated at each visit (neutrophils, panel a; fibrinogen, panel c). Raw geometric mean and standard errors estimated at each visit (CRP, panel b); the geometric mean was used as the distribution of the CRP data was skewed, thus requiring log transformation prior to calculation of the mean

CRP C-reactive protein, SE standard error