Table 1 Impulse oscillation measurements of bronchodilator response following low-dose (2 puffs, 200 μg) and standard-dose (4 puffs, 400 μg) salbutamol in healthy controls and exclusion subjects (n = 248)
From: Small airway bronchodilator response to different doses of salbutamol in 7-year-old children
Healthy controls (n = 168) | Exclusion subjects (n = 80) | |||||
|---|---|---|---|---|---|---|
Low-dose salbutamol (n = 83) | Standard-dose salbutamol (n = 85) | P value | Low-dose salbutamol (n = 41) | Standard-dose salbutamol (n = 39) | P value | |
% change in FEV1 | 5.3 (5.7) | 5.4 (5.7) | 0.984 | 9.2 (8.4) | 7.4 (7.1) | 0.317 |
Xrs5 | ||||||
Δ abs, hPa s L−1 (SD) | 0.05 (0.04) | 0.05 (0.05) | 0.984 | 0.06 (0.06) | 0.07 (0.04) | 0.169 |
Δ relative, % of baseline (SD) | −18.2 (11.3) | −18.3 (19.4) | 0.986 | −19.4 (14.4) | −26.0 (12.6) | 0.032 |
Rrs5 | ||||||
Δ abs, hPa s L−1 (SD) | −0.10 (0.06) | −0.09 (0.06) | 0.628 | −0.10 (0.08) | −0.12 (0.06) | 0.251 |
Δ relative, % of baseline (SD) | −14.5 (8.4) | −14.5 (9.3) | 0.694 | −15.7 (10.8) | −18.7 (8.2) | 0.179 |
Xrs10 | ||||||
Δ abs, hPa s L−1 (SD) | 0.06 (0.04) | 0.06 (0.04) | 0.765 | 0.06 (0.06) | 0.08 (0.04) | 0.043 |
Δ relative, % of baseline (SD) | −34.4 (19.3) | −34.8 (22.2) | 0.897 | −26.7 (50.6) | −47.1 (15.4) | 0.017 |
Rrs10 | ||||||
Δ abs, hPa s L−1 (SD) | −0.06 (0.04) | −0.05 (0.05) | 0.609 | −0.05 (0.04) | −0.07 (0.04) | 0.172 |
Δ relative, % of baseline (SD) | −10.8 (7.9) | −10.3 (8.2) | 0.679 | −10.6 (7.6) | −13.1 (6.8) | 0.126 |
AX | ||||||
Δ abs, hPa L−1 (SD) | −0.61 (0.37) | −0.58 (0.36) | 0.615 | −0.63 (0.58) | −0.81 (0.36) | 0.091 |
Δ relative, % of baseline (SD) | −32.3 (15.9) | −32.1 (18.1) | 0.950 | −28.4 (36.8) | −43.7 (12.2) | 0.015 |
Rrs20–5 | ||||||
Δ abs, hPa s L−1 (SD) | −0.06 (0.08) | −0.08 (0.05) | 0.289 | −0.06 (0.08) | −0.08 (0.05) | 0.294 |
Δrelative, % of baseline (SD) | −12.3 (75.6) | −30.3 (12.7) | 0.147 | −12.3 (75.6) | −30.3 (12.7) | 0.147 |