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Table 3 Proportion of participants with a dose shift ≥1 doubling concentration post-treatment

From: The effect of glycopyrronium and indacaterol, as monotherapy and in combination, on the methacholine dose-response curve of mild asthmatics: a randomized three-way crossover study

Time Post-Dose

LAMA, n = 15

uLABA, n = 16

Combo, n = 14

1 h

100% (15/15)

62.5% (10/16)

100% (14/14)

24 h

73.3% (11/15)

37.5% (6/16)

64.3% (9/14)

48 h

80% (12/15)

18.8% (3/16)

64.3% (9/14)

  1. LAMA, long-acting muscarinic antagonist; uLABA, ultra-long acting β2 agonist; Combo, combination therapy