LABA + ICS n = 269 | IND/GLY n = 811 | LABA OR LAMAa n = 268 | IND/GLYa n = 811 | |
---|---|---|---|---|
Patients achieved MCID in trough FEV1 (≥100 mL difference from baseline) | 90 (33.4%) | 379 (46.7%) | 74 (27.6%) | 388 (47.8%) |
Trough FEV1 responders (improvement ≥100 mL; OR [95% CI]) | 1.90 (1.42 to 2.55) | 2.53 (1.86 to 3.42) | ||
Patients achieved MCID in TDI total scores (≥1-unit difference from baseline) | 91 (33.8%) | 427 (52.7%) | 95 (35.5%) | 466 (57.5%) |
TDI responders (improvement ≥1 unit; OR [95% CI]) | 2.61 (1.94 to 3.50) | 2.85 (2.13 to 3.82) |