Fig. 5
From: Role of P2X7R in the development and progression of pulmonary hypertension
Effect of A-740003 on inflammatory status. a, b Immunohistochemical staining of macrophages with CD68 antibody in the (a) sham, (b) P/MCT vehicle group, (c) P/MCT + CA group, and (d) P/MCT + DA group and the numbers of CD68-positive macrophage cells per 20 high-power fields (HPFs). c Macrophage cell count in the bronchoalveolar lavage (BAL). d Tumour necrosis factor-α (TNF-α) and e interleukin-1β (IL-1β) in the BALF of each treatment group. Original magnification × 40. Scale bar = 50 μm for all images. *p < 0.05, **p < 0.01 compared with the sham; †p < 0.05 compared with the P/MCT vehicle group