Fig. 11
From: Role of human rhinovirus in triggering human airway epithelial-mesenchymal transition
Activation of the transcriptional repressor SLUG, but not the SNAIL or Smad2/3 pathways may contribute to EMT induced by the combination of HRV and TGF-β1. BEAS-2B cells were stimulated with medium, HRV-16, HRV-1A, TGF-β1, HRV-16 + TGF-β1, or HRV-1A + TGF-β1 for 6 h. a Representative western blot for SLUG. b Densitometry analysis for SLUG (n = 8). c Representative western blot for SNAIL. d Densitometry analysis for SNAIL (n = 6). e Representative western blot for pSMAD2/3. f Densitometry analysis for pSMAD2/3 (n = 6). Asterisk indicates significance for comparisons shown by Dunn’s post-hoc analysis after Kruskal-Wallis ANOVA. † Indicates p < 0.02 compared to medium control stimuli by Wilcoxon matched-pairs signed ranks test