Table 3 Comparison of blood, sputum and bacterial counts between baseline and exacerbation
From: Blood and sputum eosinophils in COPD; relationship with bacterial load
| Â | n | Baseline | Exacerbation | p value |
|---|---|---|---|---|
Total white blood cell count (x109/L) | 109 | 7.35 [4.40–15.60] | 8.90 [2.80–20.50] | <0.0001 |
Neutrophil blood count (x109/L) | 109 | 4.69 [2.55–12.23] | 6.01 [1.42–18.12] | <0.0001 |
Eosinophil blood count (x109/L) | 109 | 0.23 [0.04–0.90] | 0.18 [0.00–0.78] | 0.22 |
Lymphocyte blood count (x109/L) | 109 | 1.70 [0.75–4.25] | 1.80 [0.44–4.66] | 0.133 |
Monocyte blood count (x109/L) | 109 | 0.57 [0.28–1.41] | 0.70 [0.26–1.86] | <0.0001 |
Total Cell count (x106/g) | 30 | 4.07 [0.25–84.56] | 8.67 [0.41–154.5] | 0.02 |
Sputum Neutrophil cell count (x106/g) | 30 | 3.34 [0.02–82.44] | 7.20 [0.08–151.6] | 0.03 |
Sputum Macrophage cell count (x106/g) | 30 | 0.74 [0.04–4.22] | 0.09 [0.00–1.55] | <0.0001 |
Sputum Eosinophil cell count (x106/g) | 30 | 0.06 [0.00–0.52] | 0.01 [0.00–3.20] | 0.11 |
Sputum Lymphocyte cell count (x106/g) | 30 | 0.00 [0.00–0.25] | 0.00 [0.00–0.09] | 0.46 |
Sputum Epithelial cell count (x106/g) | 30 | 0.19 [0.00–2.32] | 0.17 [0.00–0.95] | 0.39 |
Sputum Neutrophil % | 30 | 77.13 [3.00–97.75] | 89.00 [5.25–99.25] | 0.04 |
Sputum Macrophage % | 30 | 15.88 [1.50–88.50] | 6.75 [0.50–70.25] | 0.02 |
Sputum Eosinophil % | 30 | 0.92 [0.00–12.75] | 0.38 [0.00–86.5] | 0.03 |
Sputum Lymphocyte % | 30 | 0.13 [0.00–2.50] | 0.00 [0.00–1.00] | 0.06 |
Sputum Epithelial cell % | 30 | 3.94 [0.00–40.00] | 2.89 [0.00–54.76] | 0.74 |
Total Bacterial Load (genome copies/ml) | 70 | 2.85 × 103 [0.0–3.69 × 1010] | 5.13 × 105 [0.0–6.09 × 108] | 0.02 |