COPD monocytes demonstrate impaired migratory ability

Respiratory Research

Table 2 Marginated CX₃CR1⁺ cells per unit vessel circumference

	COPD (n = 9)	S (n = 9)	NS (n = 6)	p value
Vessel circumference (μm)	722 (206.9)	902 (275.2)	766 (227.2)	ns
Marginated cells/vessel circumference (10^-4/μm)	10 (8)	9 (9)	20 (20)	ns
Marginated CX₃CR1⁺ (%)	3.1 (0-35.8)	48.3 (10-73.7)	85.8 (50-100)	0.0002
CX₃CR1⁺/vessel circumference (10^-4/μm)	1 (0-80)	30 (5-200)	100 (20-1000)	0.005
CX₃CR1⁺CD14⁺(Marginated CX₃CR1⁺ cells %)	0 (0-3.6)	26.7 (0-49.2)	73.4 (6.7-93.8)	0.0008
CX₃CR1⁺CD14⁺/vessel circumference (10^-4/μm)	0 (0-3)	20 (0-100)	50 (2-400)	0.002
CX₃CR1⁺CD16⁺(Marginated CX₃CR1⁺ cells %)	0 (0-29.3)	17.3 (0-60.4)	43 (20-69.9)	0.001
CX₃CR1⁺CD16⁺/vessel circumference (10^-4/μm)	0 (0-100)	10 (0-100)	100 (10-400)	0.02

This table shows CX₃CR1⁺ cells as a percentage of all marginated cells as well the absolute number of CX₃CR1⁺ cells per μm of vessel circumference (*10^-4/μm). Data is displayed as median (range). The statistical significance of differences observed was obtained using Kruskal-Wallis test with application of Dunn’s multiple comparisons test. Vessel circumference and marginated cells/μm vessel circumference are displayed as mean (SD); the statistical significance of differences observed was assessed using ANOVA with application of Tukey’s post-test

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