Fig. 7

EMT is suppressed by anti-integrin antibody and/or anti-adhesion molecule antibody. a BEAS-2B cells co-cultured with human eosinophils in the presence of anti-integrin antibodies and/or anti-ICAM-1 antibodies (anti-CD18 Ab and/or anti-CD54 Ab). b Granulocyte-macrophage colony-stimulating factor (GM-CSF) and transforming growth factor (TGF-β1) levels in the supernatant. Bars indicate mean ± SEM. c Scale bars indicate 100 μm. The data are the representative of a single experiment performed in triplicates. Two independent experiments were performed. Gene expression of E-cadherin, and vimentin in BEAS-2B cells co-cultured with eosinophils. *p < 0.01 vs eosinophils (−)/anti-CD54 (−)/anti-CD18 group; **p < 0.05 vs eosinophils (+)/anti-CD54 (−)/anti-CD18 group. Statistics by analysis of variance with Dunnett’s test