Fig. 6

EMT induced by eosinophils is suppressed by anti-integrin antibodies. a BEAS-2B cells co-cultured with human eosinophils in the presence of anti-integrin antibodies (anti-CD18 Ab and/or anti-CD29 Ab). b Gene expression of E-cadherin and vimentin in BEAS-2B cells co-cultured with human eosinophils in the presence or absence of anti-integrin antibodies (anti-CD18 Ab and/or anti-CD29 Ab). Bars indicate mean ± SEM. Scale bars indicate 100 μm. The data are the representative of a single experiment performed in triplicates. Two independent experiments were performed. *p < 0.01 vs eosinophils (−)/anti-CD29 (−)/anti-CD18 group; **p < 0.05 vs eosinophils (+)/anti-CD29 (−)/anti-CD18 group. Statistics by analysis of variance with Dunnett’s test