Fig. 1
EMT induced by EoL-1 is inhibited by procaterol. a Control and BEAS-2B cells co-cultured with EoL-1 in the presence or absence of procaterol (original magnifications, ×400). b Gene expression of E-cadherin and vimentin in BEAS-2B cells co-cultured with EoL-1 in the presence (10−9 M ~ 10−6 M) or absence of procaterol as evaluated by RT-PCR. c Granulocyte-macrophage colony-stimulating factor (GM-CSF) and transforming growth factor (TGF-β1) levels in the supernatant after co-culture in the presence (10−9 M ~ 10−6 M) or absence of procaterol. Bars indicate mean ± SEM. Scale bars indicate 100 μm. The data are the representative of a single experiment performed in triplicates. Two independent experiments were performed. *p < 0.0001 vs procaterol 0 group; **p < 0.001 and ¶p < 0.05 vs EoL-1(+)/procaterol (−) group. Statistics by analysis of variance with Dunnett’s test