Table 1 Characteristics of healthy human participants, asthmatic and COPD patients
From: Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung
Healthy volunteers (n = 967) | Bronchial asthma (n = 751) | COPD (n = 289) | |
|---|---|---|---|
Age (years) | 50.0 ± 9.1 | 57.0 ± 16.8 | 74.7 ± 8.6 |
Female (%) | 526 (54.4%) | 445 (59.3%) | 31 (10.6%) |
Smoking Index Groupa, b 0 | 607 (62.8%) | 481 (64.0%) | 10 (3.5%) |
1–200 | 126 (13.0%) | 103 (13.7%) | 9 (3.1%) |
>200 | 234 (24.2%) | 145 (19.3%) | 269 (93.1%) |
FVC (L) | 3.22 ± 0.76 | 2.92 ± 0.94 | 2.65 ± 0.87 |
FEV1 (L) | 2.68 ± 0.64 | 2.11 ± 1.06 | 1.25 ± 0.58 |
Predicted FEV1 (%) | 93.3 ± 12.1 | 85.3 ± 22.7 | 53.4 ± 22.1 |
FEV1/FVC (%) | 83.2 ± 5.2 | 71.0 ± 12.4 | 47.2 ± 12.4 |
FEV1 decline (mL/year) | 23.4 ± 49.3 (n = 742) | NA | NA |