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Table 2 Risk Factors Associated with Serum sCD14 Concentration

From: Interaction of CD14 haplotypes and soluble CD14 on pulmonary function in agricultural workers

 

sCD14 ≤ median (n = 292) N (%)

sCD14 > median (n = 292) N (%)

p-value

Age, years

 39-50

22 (8%)

16 (5%)

0.0057

 51-60

70 (24%)

47 (16%)

 

 61-70

139 (48%)

135 (46%)

 

 71-80

61 (21%)

94 (32%)

 

Sex

 Male

283 (97%)

288 (99%)

0.16

 Female

9 (3%)

4 (1%)

 

BMI

  < 25

34 (12%)

52 (18%)

0.01

 25-29.9

77 (26%)

94 (32%)

 

  ≥ 30

181 (62%)

146 (50%)

 

Race

 White

275 (95%)

280 (97%)

0.29

 Other

14 (5%)

9 (3%)

 

Education

  ≤ High School

118 (42%)

132 (48%)

0.15

  > High School

166 (58%)

145 (52%)

 

Smoking Status

 Ever

225 (78%)

238 (83%)

0.13

 Never

64 (22%)

49 (17%)

 

COPD

 No

181 (62%)

173 (59%)

0.50

 Yes

111 (38%)

119 (41%)

 

Steroid Use (Inhaled, Oral)a

 No

260 (89%)

247 (85%)

0.11

 Yes

32 (11%)

45 (15%)

 

FEV1/FVC (mean ± SD)

70.9 ± 10.1

68.4 ± 13.0

0.011

FEV1 (%) (mean ± SD)

81.8 ± 19.4

78.0 ± 22.6

0.030

Worked on a Farm, years

  < 10

48 (17%)

45 (16%)

0.23

 10-19.9

81 (28%)

77 (27%)

 

 20-29.9

54 (19%)

38 (13%)

 30+

105 (36%)

123 (43%)

 

Exposure to crops

 No

31 (11%)

39 (14%)

0.26

 Yes

257 (89%)

242 (86%)

 

Exposure to animals

 No

25 (9%)

38 (14%)

0.06

 Yes

263 (91%)

243 (86%)

 
  1. Abbreviations and Definitions: BMI body mass index (kg/m2), COPD, FEV1/FVC < 0.70
  2. aIn the last 12 months have you taken inhaled steroids (yes/no), Advair (yes/no) or Prednisone (yes/no)?