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Fig. 4 | Respiratory Research

Fig. 4

From: Differential regulation of muscle protein turnover in response to emphysema and acute pulmonary inflammation

Fig. 4

Activation of the ALP in response to pulmonary inflammation. Mice were intratracheally instilled with elastase and LPS or respective vc. Protein levels of (b) LC3B-II, (c) LC3B-I, (f) phosphorylated ULK1 (ser757), (g) total ULK1 and (i) p62 were assessed in lysates of gastrocnemius muscle tissue with western blot analysis. h Representative western blots of indicated proteins. Ratio of (a) LC3B-II over LC3B-I and (e) phosphorylated ULK1 over total ULK1. mRNA transcript levels of (d) LC3B, (j) p62, (k) Gabarapl and (l) BNIP were determined, normalized to geNorm, and expressed as fold change compared to control. n = 8–12 per group. * p < 0.05, ** p < 0.01, *** p < 0.001

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Respiratory Research

ISSN: 1465-993X

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