Fig. 1From: Differential regulation of muscle protein turnover in response to emphysema and acute pulmonary inflammationDevelopment of emphysema after instillation with elastase. Mice were intratracheally instilled with elastase to induce emphysema. a lungs were isolated 48 h after IT-LPS/NaCl and sections were stained with H&E. b μCT scans were analyzed creating a density histogram of the voxels in the selected lungs. The LAA threshold was set to −426 HU. The LAA% was calculated using the ratio of the total LAA volume (shaded area) to the total lung volume. The upper right corner shows a representative μCT image. c Changes in LAA% after IT-elastase, as determined by μCT scan analysis. n = 46 per group. d Correlation between μCT-derived LAA% and the Lm (both determined 48 h after NaCl or LPS), n = 7. *** p < 0.001Back to article page