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Table 1 Subject characteristics

From: Cluster analysis of sputum cytokine-high profiles reveals diversity in T(h)2-high asthma patients

  Asthma (n = 205) Healthy (n = 80) P value
Subjects (n=) 205 80  
Age (years) 30–40–51 23–27–42 <0.0001
Gender (M/F) 96/112 30/50 0.09
Body Mass Index 21.9–24.4–28.1 20.4–22.3–24.5 <0.0001
Active smoking (%) 25 (12%) 2 (3%) 0.007
Allergy (%) 139 (76%) 23 (35%) <0.0001
Steroid-naive 41 (20%) NA  
Inhaled steroids only 142 (69%) NA  
Inhaled and oral steroids 22 (11%) NA  
FEV1 % predicted (%) 94.6 ± 19.0 108.9 ± 14.2 <0.0001
FEV1/FVC (%) 72.3 ± 11.4 81.7 ± 6.5 <0.0001
FENO (ppb) 13.4–22.0–38.6 10.3–16.2–22.9 0.0004
Sputum eosinophils (%) 0.0–1.0–4.0 0.0–0.0–0.4 <0.0001
Sputum neutrophils (%) 13.0–35.0–58.8 13.8–25.4–41.1 0.02
Sputum total cell count (x106 cells) 0.8–1.3–2.5 0.9–1.4–2.0 0.48
Asthma Control test (/25) 17.0–20.5–23.0 25–25–25 <0.0001
  1. Clinical, lung function and inflammatory parameters in asthmatic patients and healthy subjects. Normally distributed data were represented as mean ± standard deviation and analyzed by T-test. Data that were not normally distributed were represented as median and 25–75% (interquartile range) percentile and analyzed by Mann-Whitney test. FEV 1 Forced Expiratory Volume in 1 second, FVC Forced Vital Capacity, F E NO Fraction of exhaled Nitric Oxide