Methacholine (mg/mL) | 0 | 1 | 6 | 12 | 25 |
---|---|---|---|---|---|
PBS/OVA/Vehicle | 0.93 ± 0.19 | 1.57 ± 0.15 | 2.22 ± 0.20 | 2.93 ± 0.3.3 | 3.95 ± 0.53 |
OVA/OVA/Vehicle | 1.19 ± 0.26 | 2.63 ± 0.51 | 5.31 ± 0.52* | 7.25 ± 0.45* | 11.27 ± 0.87* |
OVA/OVA/NEt-4IB 0.0015% | 0.82 ± 0.05 | 2.14 ± 0.31 | 4.26 ± 0.59 | 5.81 ± 0.73 | 9.93 ± 1.66 |
OVA/OVA/NEt-4IB 0.005% | 0.84 ± 0.10 | 1.66 ± 0.20 | 3.97 ± 0.44 | 6.07 ± 0.41 | 8.75 ± 0.56 |
OVA/OVA/NEt-4IB 0.015% | 1.00 ± 0.15 | 2.10 ± 0.25 | 3.57 ± 0.52 | 5.28 ± 0.37** | 7.14 ± 0.31** |
OVA/OVA/PSL 0.005% | 0.89 ± 0.06 | 1.52 ± 0.10 | 3.13 ± 0.34** | 4.73 ± 0.47** | 6.38 ± 0.42** |