From: The role of serum procalcitonin in establishing the diagnosis and prognosis of pleural infection
Serum biomarker | Sensitivity | Specificity | Positive predictive value | Negative predictive value | Positive likelihood ratio | Negative likelihood ratio | ||
---|---|---|---|---|---|---|---|---|
PCT | AUC calculated optimal cut-off value | ≥0.085 μg/l | 0.69 | 0.80 | 0.46 | 0.91 | 3.36 | 0.39 |
Manufacturers recommended cut-off value | ≥0.05 μg/l | 0.78 | 0.66 | 0.37 | 0.92 | 2.27 | 0.34 | |
WCC | AUC calculated optimal cut-off value | ≥10.35x109/L | 0.69 | 0.80 | 0.46 | 0.91 | 3.36 | 0.39 |
CRP | AUC calculated optimal cut-off value | ≥46.5 mg/l | 0.88 | 0.67 | 0.41 | 0.95 | 2.69 | 0.19 |