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Fig. 5 | Respiratory Research

Fig. 5

From: Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation

Fig. 5

Influence of NAC on the cytokines release (a IL-1β concentrations, b IL-6 concentrations, c IL-8 concentrations and d TNF-α concentrations) induced by overnight incubation of human isolated bronchi with LPS (100 ng/ml). Horizontal dotted lines indicate the cytokines concentrations in control bronchi (c), in bronchi treated with LPS alone or in the presence of GSH. Data are expressed as the mean ± SEM of experiments repeated in triplicate. **P < 0.01 and ***P < 0.001 vs. LPS-incubated bronchi (statistical significance assessed by two-way ANOVA)

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