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Fig. 4 | Respiratory Research

Fig. 4

From: Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation

Fig. 4

Influence of NAC on the anti-oxidant response (a total anti-oxidant capacity [TAC], b GSH concentrations and c superoxide dismutase [SOD] activity) induced by overnight incubation of human isolated bronchi with LPS (100 ng/ml). Horizontal dotted lines indicate the anti-oxidant response in control bronchi (c), in bronchi treated with LPS alone or in the presence of GSH. In B the LPS + GSH treatment has been not carried out in order to not influence the GSH quantification. Data are expressed as the mean ± SEM of experiments repeated in triplicate. ***P < 0.001 vs. LPS-incubated bronchi (statistical significance assessed by two-way ANOVA). ND: not detectable

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