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Table 1 Baseline characteristics of the subgroups with and without diabetes

From: Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort

Parameter Non-diabetes patients Diabetes patients (extended def.) p-values (extended def.) Diabetes patients (restrictive def.) p-values (restrictive def.)
Gender (m/f) 1270/947(57/43%) 262/96 (73/27%) p < 0.001* 208/69 (76/24%) p < 0.001*
Age (y) 64.7 (±8.7) 67.0 (±7.6) p < 0.001* 67.1 (±7.5) p < 0.001*
BMI (kg/m2) 26.4 (±5.05) 30.5 (±5.8) p < 0.001* 30.69 (±5.1) p < 0.001*
Waist circumf. (cm) 97.7 (±15.1) 110.0 (±14.7) p < 0.001* 111.1 (±14.3) p < 0.001*
Packyears 46.8 (±34.8) 55.3 (±40.9) p < 0.001* 55.4 (±40.5) p < 0.001*
Hb (mg/dl) 14.66 (±1.38) 14.43 (±1.39) p = 0.003* 14.46 (±1.32) p = 0.032*
HbA1c (%) 5.76 (±0.47) 6.91 (±1.0) p < 0.001* 7.03(±1.13) p < 0.001*
Creatinine (mg/dl) 0.88 (±0.25) 0.96 (±0.29) p < 0.001* 0.95 (±0.27) p < 0.001*
FEV1%pred 59.7 (±22.2) 59.8 (±21.2) p = 0.906 59.6 (±20.0) p = 0.973
FEV1/FVC 54.8 (±13.6) 55.3 (±13.2) p = 0.431 54.5 (±13.0) p = 0.687
FVC%pred 78.6 (±19.1) 79.1 (±19.1) p = 0.638 78.0 (±18.7) p = 0.223
TLC%pred 112.9 (±30.4) 107.2 (±27.6) p < 0.001* 106.3(±27.3) p < 0.001*
RV%pred 150.1 (±47.2) 143.4 (±45.2) p = 0.012* 142.4 (±43.5) p ≤ 0.011*
ITGV%pred 146.6 (±36,8) 135.1 (±36.0) p < 0.001* 134.5 (±35.3) p < 0.001*
TLCO%pred 52.8 (±21.0) 57.1 (±19.6) p < 0.001* 57.0 (±19.2) p = 0.001*
KCO%pred 66.1 (±23.8) 75.6 (±23.4) p < 0.001* 76.3 (±23.6) p < 0.001*
GOLD 0/1/2/3/4 269/242/868/679/159 (12/11/39/31/7%) 68/33/133/103/21 (19/9/37/29/6%) p = 0.010* 51/26/107/78/15 (18/9/39/28/5%) p = 0.066
GOLD A/B/C/D 239/1198/32/735 (11/54/2/33%) 37/170/12/138 (10/48/3/39%) p = 0.008* 32/130/10/104 (12/47/4/38%) p = 0.017*
  1. The table shows mean values and standard deviations or absolute numbers, in case of gender and COPD classes additionally percentages (deviations of total from 100% are due to rounding). Column 3 shows the results of comparisons between the diabetes group (extended definition) and the complementary group of non-diabetes patients. Column 5 shows the corresponding results of comparisons between diabetes group (restrictive definition) and the corresponding group of non-diabetes patients. The comparisions between groups were performed by unpaired t-tests, either for equal or unequal variances depending on the data, or by chi-square-tests in the case of categorical variables
  2. Significant (p < 0.05) differences are marked with (*)