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Fig. 3 | Respiratory Research

Fig. 3

From: Atrial natriuretic peptide protects against bleomycin-induced pulmonary fibrosis via vascular endothelial cells in mice

Fig. 3

ANP attenuates the elevated mRNA levels of pro-inflammatory and pro-fibrotic cytokines in BLM-administered mice. Quantitative RT-PCR analysis of IL-6 (a), MCP-1 (b), bFGF (c), collagen 1A (d), TIMP1 (e), TGF-β (f), and IL-1β (g) in lung tissues 21 days after BLM administration. Relative mRNA level of each cytokine in normal control or BLM/vehicle-treated or BLM/ANP-treated mice are shown. Values represent means ± SEMs (n = 5 mice per group). *p < 0.05

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